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Download CRISPR: Genome Editing and Engineering And Related Issues PDF

CRISPR: Genome Editing and Engineering And Related Issues


Author :
Publisher : Gale, Cengage Learning
Release Date :
ISBN 10 : 9780028666686
Pages : 11 pages
File Format : PDF, EPUB, TEXT, KINDLE or MOBI
Rating : 4.6/5 (668 users download)

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Summary Book Review CRISPR: Genome Editing and Engineering And Related Issues by Barbara Wexler:

Download or read book CRISPR: Genome Editing and Engineering And Related Issues written by Barbara Wexler and published by Gale, Cengage Learning. This book was released on 2018-11-16 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: eBook content that offers a clear and comprehensive introduction to CRISPR and related topics. Entries include foundational concepts, key scientific figures and historical themes, ethical issues , and advances in the science.

Download Genome Editing and Engineering PDF

Genome Editing and Engineering


Author :
Publisher : Cambridge University Press
Release Date :
ISBN 10 : 9781316762080
Pages : pages
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Rating : 4.6/5 (28 users download)

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Summary Book Review Genome Editing and Engineering by Krishnarao Appasani:

Download or read book Genome Editing and Engineering written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2018-06-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting.

Download Genome Engineering via CRISPR-Cas9 System PDF

Genome Engineering via CRISPR-Cas9 System


Author :
Publisher : Academic Press
Release Date :
ISBN 10 : 9780128181416
Pages : 384 pages
File Format : PDF, EPUB, TEXT, KINDLE or MOBI
Rating : 4.8/5 (141 users download)

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Summary Book Review Genome Engineering via CRISPR-Cas9 System by Vijai Singh:

Download or read book Genome Engineering via CRISPR-Cas9 System written by Vijai Singh and published by Academic Press. This book was released on 2020-02-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields. Provides basic understanding and a clear picture on how to design, use and implement the CRISPR-Cas9 system in different organisms Explains how to create an animal model for disease research and screening purposes using CRISPR Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, neurology, cancer, industry, and many more

Download Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B PDF

Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B


Author :
Publisher : Academic Press
Release Date :
ISBN 10 : 9780323852982
Pages : 198 pages
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Rating : 4.5/5 (298 users download)

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Summary Book Review Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B by :

Download or read book Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B written by and published by Academic Press. This book was released on 2021-04-29 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems Part B, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume mainly covers insect cell line, protozoans, zebrafish, drosophila, CRISPRi, patents as well as technology transfer, and many more. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas. Offers basic understanding and a clear picture of genome editing CRISPR-Cas systems in different organisms Explains how to create an animal model for disease diagnosis/research and reprogram CRISPR for insect cell line, protozoans, zebrafish, drosophila, and many more Discusses the advances, patents, applications, challenges and opportunities in CRISPR-Cas9 systems in basic sciences, biomedicine, molecular biology and many more

Download Precision Medicine, CRISPR, and Genome Engineering PDF

Precision Medicine, CRISPR, and Genome Engineering


Author :
Publisher : Springer
Release Date :
ISBN 10 : 9783319639048
Pages : 178 pages
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Rating : 4.3/5 (94 users download)

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Summary Book Review Precision Medicine, CRISPR, and Genome Engineering by Stephen H. Tsang:

Download or read book Precision Medicine, CRISPR, and Genome Engineering written by Stephen H. Tsang and published by Springer. This book was released on 2017-11-11 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.

Download Development and Application of Novel Genome Engineering Tools in Microbial Biotechnology PDF

Development and Application of Novel Genome Engineering Tools in Microbial Biotechnology


Author :
Publisher : Frontiers Media SA
Release Date :
ISBN 10 : 9782889664054
Pages : pages
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Rating : 4.6/5 (45 users download)

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Summary Book Review Development and Application of Novel Genome Engineering Tools in Microbial Biotechnology by Jiazhang Lian:

Download or read book Development and Application of Novel Genome Engineering Tools in Microbial Biotechnology written by Jiazhang Lian and published by Frontiers Media SA. This book was released on 2021-01-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Genome Engineering for Crop Improvement PDF

Genome Engineering for Crop Improvement


Author :
Publisher : John Wiley & Sons
Release Date :
ISBN 10 : 9781119672364
Pages : 416 pages
File Format : PDF, EPUB, TEXT, KINDLE or MOBI
Rating : 4.7/5 (236 users download)

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Summary Book Review Genome Engineering for Crop Improvement by Santosh Upadhyay:

Download or read book Genome Engineering for Crop Improvement written by Santosh Upadhyay and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, significant advancements have been made in the management of nutritional deficiency using genome engineering—enriching the nutritional properties of agricultural and horticultural crop plants such as wheat, rice, potatoes, grapes, and bananas. To meet the demands of the rapidly growing world population, researchers are developing a range of new genome engineering tools and strategies, from increasing the nutraceuticals in cereals and fruits, to decreasing the anti-nutrients in crop plants to improve the bioavailability of minerals and vitamins. Genome Engineering for Crop Improvement provides an up-to-date view of the use of genome editing for crop bio-fortification, improved bioavailability of minerals and nutrients, and enhanced hypo-allergenicity and hypo-immunogenicity. This volume examines a diversity of important topics including mineral and nutrient localization, metabolic engineering of carotenoids and flavonoids, genome engineering of zero calorie potatoes and allergen-free grains, engineering for stress resistance in crop plants, and more. Helping readers deepen their knowledge of the application of genome engineering in crop improvement, this book: Presents genetic engineering methods for developing edible oil crops, mineral translocation in grains, increased flavonoids in tomatoes, and cereals with enriched iron bioavailability Describes current genome engineering methods and the distribution of nutritional and mineral composition in important crop plants Offers perspectives on emerging technologies and the future of genome engineering in agriculture Genome Engineering for Crop Improvement is an essential resource for academics, scientists, researchers, agriculturalists, and students of plant molecular biology, system biology, plant biotechnology, and functional genomics.

Download Modern Tools for Genetic Engineering PDF

Modern Tools for Genetic Engineering


Author :
Publisher : BoD – Books on Demand
Release Date :
ISBN 10 : 9789535123927
Pages : 226 pages
File Format : PDF, EPUB, TEXT, KINDLE or MOBI
Rating : 4.2/5 (392 users download)

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Summary Book Review Modern Tools for Genetic Engineering by Michael Kormann:

Download or read book Modern Tools for Genetic Engineering written by Michael Kormann and published by BoD – Books on Demand. This book was released on 2016-05-18 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible. This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun.

Download Rice Genome Engineering and Gene Editing PDF

Rice Genome Engineering and Gene Editing


Author :
Publisher : Humana
Release Date :
ISBN 10 : 1071610678
Pages : 378 pages
File Format : PDF, EPUB, TEXT, KINDLE or MOBI
Rating : 4.7/5 (161 users download)

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Summary Book Review Rice Genome Engineering and Gene Editing by Anindya Bandyopadhyay:

Download or read book Rice Genome Engineering and Gene Editing written by Anindya Bandyopadhyay and published by Humana. This book was released on 2021-01-21 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores rice molecular biology, genetic engineering, and genome editing technologies. Dividing into three parts, the book covers subjects such as genetic engineering and tissue culture of rice, including efficient methods for rice transformation and regeneration, genome editing, targeted integration, and gene stacking in rice, including multiple methods utilizing CRISPR systems for targeted gene knock-out or genome modification via base editing, and diverse methods describing bioinformatic, molecular, and cellular analyses in rice. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Rice Genome Engineering and Gene Editing: Methods and Protocols serves as a valuable resource for researchers worldwide striving to further their efforts on advancing research and producing genetically improved rice varieties.

Download Genome Editing PDF

Genome Editing


Author :
Publisher : Springer
Release Date :
ISBN 10 : 9783319341484
Pages : 166 pages
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Rating : 4.4/5 (148 users download)

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Summary Book Review Genome Editing by Kursad Turksen:

Download or read book Genome Editing written by Kursad Turksen and published by Springer. This book was released on 2016-08-09 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions. Genome Editing is an essential, of-the-moment contribution to this rapidly growing field. Drawing from a wealth of international perspectives, it presents novel techniques and applications for the engineering of the human genome. This book is essential reading for all clinicians and researchers in stem cells, regenerative medicine, genomics, biochemical and biomedical engineering- especially those interested in learning more about genome editing and applying it in a targeted, specific way.

Download Natural Genetic Engineering and Natural Genome Editing, Volume 1178 PDF

Natural Genetic Engineering and Natural Genome Editing, Volume 1178


Author :
Publisher : Wiley-Blackwell
Release Date :
ISBN 10 : STANFORD:36105213127959
Pages : 276 pages
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Rating : 4./5 ( users download)

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Summary Book Review Natural Genetic Engineering and Natural Genome Editing, Volume 1178 by Günther Witzany:

Download or read book Natural Genetic Engineering and Natural Genome Editing, Volume 1178 written by Günther Witzany and published by Wiley-Blackwell. This book was released on 2009-11-23 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume presents manuscripts stemming from the conference "Natural Genetic Engineering and Natural Genome Editing" held on July 3-6, 2008 ... Salzburg, Austria"-- page V.

Download Gene Editing in Plants PDF

Gene Editing in Plants


Author :
Publisher : Academic Press
Release Date :
ISBN 10 : 9780128117446
Pages : 264 pages
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Rating : 4.1/5 (744 users download)

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Summary Book Review Gene Editing in Plants by :

Download or read book Gene Editing in Plants written by and published by Academic Press. This book was released on 2017-08-31 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Editing in Plants, Volume 149 aims to provide the reader with an up-to-date survey of cutting-edge research with gene editing tools and an overview of the implications of this research on the nutritional quality of fruits, vegetables and grains. New chapters in the updated volume include topics relating to Genome Engineering and Agriculture: Opportunities and Challenges, the Use of CRISPR/Cas9 for Crop Improvement in Maize and Soybean, the Use of Zinc-Finger Nucleases for Crop Improvement, Gene Editing in Polyploid Crops: Wheat, Camelina, Canola, Potato, Cotton, Peanut, Sugar Cane, and Citrus, and Gene Editing With TALEN and CRISPR/Cas in Rice. This ongoing serial contain contributions from leading scientists and researchers in the field of gene editing in plants who describe the results of their own research in this rapidly expanding area of science. Shows the importance of revolutionary gene editing technology on plant biology research and its application to agricultural production Provides insight into what may lie ahead in this rapidly expanding area of plant research and development Contains contributions from major leaders in the field of plant gene editing

Download How Genome Editing is Revolutionizing Medicine PDF

How Genome Editing is Revolutionizing Medicine


Author :
Publisher : GRIN Verlag
Release Date :
ISBN 10 : 9783346558978
Pages : 56 pages
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Rating : 4.5/5 (897 users download)

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Summary Book Review How Genome Editing is Revolutionizing Medicine by Gunnar Keller:

Download or read book How Genome Editing is Revolutionizing Medicine written by Gunnar Keller and published by GRIN Verlag. This book was released on 2021-12-20 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bachelor Thesis from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 1,1, Management Center Innsbruck, course: Biotechnology, language: English, abstract: CRISPR continues to drive the world of gene editing. About seven years ago, scientists reported that CRISPR technology can enable precise and efficient genome editing in living eukaryotic cells. Since then, interest in the method has spread extensively across the globe. Not long after its sudden headstart in 2013, already thousands of laboratories started taking up the technique and investors began funding startups to harness its potential. This ultimately resulted in major improvements being made in incredibly short periods of time. Simultaneously, this also initiated and continues to drive an increasing gap between new innovative applications in the field of gene editing and the overall awareness of the general public. Ethical concerns have remained a steady companion of this rise. With myriads of research papers about CRISPR related topics being published every year, trying to stay on top of developments can be a cumbersome task. The goal of this paper is to summarize current practice and research areas that are part of modern gene editing. Following a brief summary of CRISPR basics, used endonucleases and techniques, its impact on the treatment of hereditary diseases, viral infections and cancer is illustrated based on recent examples. Effects of gene editing on cell line engineering efforts are described using studies focusing on glycosylation, impurities, cultivation and production efficiency issues of CHO cell lines. Besides discussing CRISPR applications for rapid SARS-CoV-2 diagnosis, current challenges for clinical use including off-targets, immune responses and lacking drug delivery efficiencies as well as promising developments are being reviewed. This paper is supposed to support quick elucidation of future potential of the rapidly evolving world of CRISPR Cas genome editing and facilitate retrieval of further literature.

Download Redesigning Life PDF

Redesigning Life


Author :
Publisher : Oxford University Press
Release Date :
ISBN 10 : 9780191079719
Pages : 320 pages
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Rating : 4.7/5 (971 users download)

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Summary Book Review Redesigning Life by John Parrington:

Download or read book Redesigning Life written by John Parrington and published by Oxford University Press. This book was released on 2016-07-07 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the birth of civilisation, human beings have manipulated other life-forms. We have selectively bred plants and animals for thousands of years to maximize agricultural production and cater to our tastes in pets. The observation of the creation of artificial animal and plant variants was a key stimulant for Charles Darwin's theory of evolution. The ability to directly engineer the genomes of organisms first became possible in the 1970s, when the gene for human insulin was introduced into bacteria to produce this protein for diabetics. At the same time, mice were modified to produce human growth hormone, and grew huge as a result. But these were only our first tottering steps into the possibilities of genetic engineering. In the past few years, the pace of progress has accelerated enormously. We can now cut and paste genes using molecular scissors with astonishing ease, and the new technology of genome editing can be applied to practically any species of plants or animals. 'Mutation chain reaction' can be used to alter the genes of a population of pests, such as flies; as the modified creatures breed, the mutation is spread through the population, so that within a few generations the organism is almost completely altered. At the same time, scientists are also beginning to synthesize new organisms from scratch. These new technologies hold much promise for improving lives. Genome editing has already been used clinically to treat AIDS patients, by genetically modifying their white blood cells to be resistant to HIV. In agriculture, genome editing could be used to engineer species with increased food output, and the ability to thrive in challenging climates. New bacterial forms may be used to generate energy. But these powerful new techniques also raise important ethical dilemmas and potential dangers, pressing issues that are already upon us given the speed of scientific developments. To what extent should parents be able to manipulate the genetics of their offspring - and would designer babies be limited to the rich? Can we effectively weigh up the risks from introducing synthetic lifeforms into complex ecosystems? John Parrington explains the nature and possibilities of these new scientific developments, which could usher in a brave, new world. We must rapidly come to understand its implications if we are to direct its huge potential to the good of humanity and the planet.

Download CRISPR/Cas Genome Editing PDF

CRISPR/Cas Genome Editing


Author :
Publisher : Springer Nature
Release Date :
ISBN 10 : 9783030420222
Pages : 220 pages
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Rating : 4.2/5 (22 users download)

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Summary Book Review CRISPR/Cas Genome Editing by Anjanabha Bhattacharya:

Download or read book CRISPR/Cas Genome Editing written by Anjanabha Bhattacharya and published by Springer Nature. This book was released on 2020-12-11 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive collection of papers on CRISPR/Cas genome editing in connection with agriculture, climate-smart crops, food security, translational research applications, bioinformatics analysis, practical applications in cereals, floriculture crops, engineering plants for abiotic stress resistance, the intellectual landscape, regulatory framework, and policy decisions. Gathering contributions by internationally respected experts in the field of CRISPR/Cas genome editing, the book offers an essential guide for researchers, students, teachers and scientists in academia; policymakers; and public companies, private companies and cooperatives interested in understanding and/or applying CRISPR/Cas genome editing to develop new agricultural products.

Download Genome Editing PDF

Genome Editing


Author :
Publisher : Springer
Release Date :
ISBN 10 : 9781493935093
Pages : 263 pages
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Rating : 4.3/5 (59 users download)

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Summary Book Review Genome Editing by Toni Cathomen:

Download or read book Genome Editing written by Toni Cathomen and published by Springer. This book was released on 2016-03-04 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular diseases, phase integrases, triplex forming oligonucleotides and peptide nucleic acids, aptamer-guided gene targeting, AAV gene editing via DSB repair, engineered nucleases and trinucleotide repeat diseases, and creation of HIV-resistant cells. The expertly authored chapters contextualize current developments within the history of genome editing while also discussing the current and potential safety concerns of this rapidly growing field. Genome Editing: The Next Step in Gene Therapy, the latest volume in the American Society of Gene and Cell Therapy series, deftly illuminates the potential of genetic engineering technology to eradicate today’s deadliest and most prolific diseases. It is ideal reading for clinicians and researchers in genetics and immunology.

Download Human Genome Editing PDF

Human Genome Editing


Author :
Publisher : National Academies Press
Release Date :
ISBN 10 : 9780309452885
Pages : 328 pages
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Rating : 4.5/5 (288 users download)

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Summary Book Review Human Genome Editing by National Academies of Sciences, Engineering, and Medicine:

Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.